English Name |
Anti-KDR Polyclonal Antibody |
Chinese Name |
血管内皮生长因子受体2抗体 |
Target |
KDR |
Synonym |
VEGF Receptor 2, CD309, CD309 antigen, Fetal liver kinase 1, FLK-1, FLK1, KDR, Kinase insert domain receptor (a type III receptor tyrosine kinase), Kinase insert domain receptor, KRD1, Ly73, Protein tyrosine kinase receptor FLK1, Protein-tyrosine kinase receptor flk-1, Tyrosine kinase growth factor receptor, Vascular endothelial growth factor receptor 2, VEGFR 2, VEGFR, VEGFR-2, VEGFR2, VGFR2_HUMAN |
Backgroud |
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. |
Swiss Prot |
P35968 |
Gene ID |
3791 |
Subcellular Localization |
Cell junction Cell membrane Cytoplasm Cytoplasmic vesicle Early endosome Endoplasmic reticulum Nucleus Secreted Single-pass type I membrane protein |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
75/79/151kDa |
Dilution Ratio |
WB 1:100-500. IHC 1:50-200. |
Immunogen |
Recombinant protein of human KDR |
Public Immunogen Range |
1147-1356aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Mouse Rat |
Application |
WB IHC |
Specification |
50ul 100ul |