{{cart_num}}
My CartReactivity：Human
Application：IHC,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：5371
Host：Rabbit
Qty：
Size：
| Name | Anti-PML Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-2000.IHC 1:50-200 |
| Target | PML |
| Background | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Swiss Prot | P29590 |
| Gene ID | 5371 |
| Subcellular Location | Cytoplasm Cytoplasmic side Early endosome membrane Endoplasmic reticulum membrane Nucleus PML body Peripheral membrane protein nucleolus nucleoplasm |
| Immunogen | Recombinant protein of human PML |
| Public Immunogen Range | 300-600aa |
| Calculated MW | 98kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Human |
| Application | IHC WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded ovarian cancer��hu��/pancreatic cancer(hu) using PML antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with PML antibody diluted at 1:1000;Lane: HeLa cells.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
