English Name |
Anti-RRBP1 Polyclonal Antibody |
Chinese Name |
核糖体结合蛋白1抗体 |
Target |
RRBP1 |
Synonym |
180 kDa ribosome receptor homolog, DKFZp586A1420, ES/130, ES/130 related protein, ES130, FLJ36146, hES, Ribosome binding protein 1, Ribosome binding protein 1 homolog 180kDa, Ribosome binding protein 1 homolog, Ribosome receptor protein, RRBP 1, RRp, RRBP1_HUMAN |
Backgroud |
This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. |
Swiss Prot |
Q9P2E9 |
Gene ID |
6238 |
Subcellular Localization |
Endoplasmic reticulum membrane Single-pass type III membrane protein |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
152kDa |
Dilution Ratio |
WB 1:500-2000. IF 1:50-200 |
Immunogen |
Recombinant protein of human RRBP1 |
Public Immunogen Range |
1-140aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Mouse |
Application |
WB IF |
Specification |
50ul 100ul |