English Name |
Anti-KLRC1 Polyclonal Antibody |
Chinese Name |
NK细胞受体2A抗体 |
Target |
KLRC1 |
Synonym |
KLRC1, C lectin type II protein, CD159 antigen like family member A, CD159A, Killer cell lectin like receptor subfamily C member 1, MGC13374, MGC59791, Natural killer cell lectin, Natural killer group protein 2, NK cell receptor A, NKG2 1/B activating NK receptor, NKG2 A/B activating NK receptor, NKG2 A/B type II integral membrane protein, NKG2, NKG2A_HUMAN, NKG2-A/NKG2-B type II integral membrane protein, NKG2-A/B-activating NK receptor, NKG2A |
Backgroud |
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Swiss Prot |
P26715 |
Gene ID |
3821 |
Subcellular Localization |
Membrane Single-pass type II membrane protein |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
26kDa |
Dilution Ratio |
WB 1:500-2000. |
Immunogen |
Recombinant protein of human KLRC1 |
Public Immunogen Range |
96-215aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Mouse |
Application |
WB |
Specification |
50ul 100ul |