Anti-SMN2 Polyclonal Antibody_Primary Antibodies_Antibodies_Solarbio-Global Leader in Antibody and Elisa Kit

Biochemical Reagents

Antibiotics Vitamins Animal & Plant Hormones Acids & Salts & Amines Carbohydrates and Derivatives Lipids & Fatty Acid Derivatives Nucleic Acids & Nucleotides & Derivatives Amino Acids & Protein Enzymes & Coenzymes Surfactants & Detergents & Chelators Other Biochemical Reagents Universal Buffer

Protein and Immunity

Protein Extraction/Quantification Protein Electrophoresis Other Reagents Immunotechnical Services Recombinant Protein Whole Cell Protein

Small Molecule Compounds

Star Products Inhibitors & Antagonists & Agonists Peptide PROTAC Anti-Infection Plant Hormones Amino Acids & Derivatives Vitamins & Derivatives Carbohydrates & It's Analogues Cosolvent & Solubilizer Dye & Probe Reaction Substrate & Physicochemical Detection Mini Compound Kits Experimental Solution

Antibodies

Primary Antibodies Secondary Antibodies Loading Control Antibodies Label Antibodies Antigens Plant Antibodies Viral Antibodies Bacterial Antibodies Small Molecule Antibodies RNA Antibodies

ELISA

Human Rats Mouse Other Species Antibody Pairs Related Auxiliary Reagent Common Species Unpackaged Kit

Biochemical Assay Kits

REDOX Series Energy Metabolism Series Carbohydrate Metabolism Series Fatty Acid Metabolism Series Nitrogen Metabolism Series Protein ＆ Enzyme Series Other Biochemical Series

Standard References

Star Standard References Control Herbs Standard Solution CP Standards Imported Standards Standard Reference Derivatization Reagent Ion Pair Reagents Domestic Standard Material UV Spectroscopy Standards

Dye Reagents

Dye Fluorescent Stain HE Stain Tissue Stain Plant Stain Enzymatic Stain Special Cell Stain Intracellular Component Stain Microbial Stain Auxiliary Reagent Section Preparation Reagent

Cell Biology

Cell Detection Reagents Cell Growth Factor Cell Line Cell Culture Cell Isolation & Digestion Cell Staining & Probe Cell Transfection Limulus Lysate

Molecular Biology

Nucleic Acid Extraction/Purification PCR Nucleic Acid Electrophoresis Recombinant Clone Expression Molecular Hybridization

Chromatography Media

Fillers Prepacked Column

Microbial Culture

Strains Drug Sensi-Disc Culture Medium Other Microbial Medium

Instruments & Consumables

Common Consumables Imported Consumables Pipette Instruments Consignment Products

Magnetic Beads

Purified Magnetic Beads Immunoprecipitation Base Magnetic Beads

Nanomaterials

Graphite/Graphene Carbon Nanomaterials Molecular Sieve Other Nanomaterials Inorganic Nanomaterials Metallic Nanomaterial Graphenoid

Peptides

Substance P & Related Peptides Pituitary Adenylate Cyclase Activating Peptides Bag Cell Peptides Cholecystokinin RGD/RAD Peptides Opioid Peptides Cancer Research Apelin/APLN Viral-Associated Peptides Laminin Peptides Pituitary & Hypothalamic Hormone Melanocyte-Stimulating Hormone/MSH Adrenocorticotropic Hormone/ACTH Growth-Promoting Hormone Neuropeptides Thymopoietin & Thymosin Peptides Endothelin & It's Analogues Protein Kinases & Related Peptides Amyloid Peptides Multiple Sclerosis Peptide Tag Osteoporosis Research Matrix Metalloproteinase Substrate Hormones Calcitonin Antimicrobial Peptides Antioxidant Peptides Insect Neuropeptides Casein Morphine Peptides Enzyme Substrate Peptides Prolactin-Releasing Peptides Enkephalin Brain Natriuretic Peptides Endorphin & Endorphin Thrombin-Related Peptides Others Peptides Dynorphin Neurokinin Neuropeptides & Related Peptides Renal Myelin Peptides Growth Hormone & Growth Factor Somatostatin & It's Analogues Leptin Fragment Peptides Bombesin Gastrin Cell-Penetrating Peptides Fibronectin & Extracellular Matrix Peptides Anti-Inflammatory Peptides Natriuretic Peptides A Angiotensinogen Substrates & Inhibitors Angiopoietin & Angiotensin Bradykinin Thrombospondin Hematology Inflammation Research Allatostatins Inhibitor-Related Peptides Cosmetic Peptides

Chemical Synthesis

PEG Derivatives Building Blocks

SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
K002594P-100ul	Inquiry	Inquiry	Inquiry	Inquiry
K002594P-50ul	Inquiry	Inquiry	Inquiry	Inquiry

English Name	Anti-SMN2 Polyclonal Antibody
Chinese Name	运动神经元生存蛋白抗体
Target	SMN2
Synonym	SMNT;BCD541;C-BCD541;GEMIN1;SMNC;TDRD16B; survival motor neuron protein;Gemin 1
Backgroud	This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein. While mutations in the telomeric copy are associated with spinal muscular atrophy, mutations in this gene, the centromeric copy, do not lead to disease. This gene may be a modifier of disease caused by mutation in the telomeric copy. The critical sequence difference between the two genes is a single nucleotide in exon 7, which is thought to be an exon splice enhancer. Note that the nine exons of both the telomeric and centromeric copies are designated historically as exon 1, 2a, 2b, and 3-8. It is thought that gene conversion events may involve the two genes, leading to varying copy numbers of each gene. The full length protein encoded by this gene localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein. Four transcript variants encoding distinct isoforms have been described.
Swiss Prot	Q16637
Gene ID	6607
Subcellular Localization	Cell projection Cytoplasm Nucleus
Host	Rabbit
Clone Type	Polyclonal Antibody
Subtype	IgG
Protein MW	32/29/30/27kDa
Dilution Ratio	WB 1:500-2000. IF 1:50-200.
Immunogen	Recombinant protein of human SMN2
Public Immunogen Range	1-197aa
Purification Method	Affinity purification
Storage Buffer	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage	Store at -20℃, avoid freeze/thaw cycles.
Unit	Piece
Cross-Reactivity	Human Mouse Rat
Application	WB IF
Specification	50ul 100ul