English Name |
Anti-DTNBP1 Polyclonal Antibody |
Chinese Name |
肌萎缩dystrobrevin结合蛋白1抗体 |
Target |
DTNBP1 |
Synonym |
Dysbindin-1, 5430437B18Rik, AW048963, dysbindin, sdy, DTNBP1, Dystrobrevin binding protein 1, Hermansky Pudlak syndrome 7 protein, HPS7, DTBP1_HUMAN, Dystrobrevin-binding protein-1, Hermansky-Pudlak syndrome 7 protein, HPS7 protein |
Backgroud |
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene. |
Swiss Prot |
Q96EV8 |
Gene ID |
84062 |
Subcellular Localization |
Cell junction Cytoplasm Cytoplasmic side Cytoplasmic vesicle Cytoplasmic vesicle membrane Endoplasmic reticulum Endosome membrane Melanosome membrane Nucleus Nucleus Peripheral membrane protein postsynaptic cell membrane postsynaptic density secretory vesicle synapse synaptic vesicle membrane |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
39kDa |
Dilution Ratio |
WB 1:500-2000. |
Immunogen |
Recombinant protein of human DTNBP1 |
Public Immunogen Range |
1-351aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Mouse |
Application |
WB |
Specification |
50ul 100ul |