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My CartReactivity：Rat,Mouse,Human
Application：IF,IHC,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：6624
Host：Rabbit
Qty：
Size：
| Name | Anti-FSCN1 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-2000. IHC 1:50-200. |
| Target | FSCN1 |
| Background | This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. |
| Swiss Prot | Q16658 |
| Gene ID | 6624 |
| Subcellular Location | Cell junction Cell projection Cytoplasm cytoskeleton cytosol filopodium invadopodium microvillus |
| Immunogen | Recombinant protein of human FSCN1 |
| Public Immunogen Range | 394-493aa |
| Calculated MW | 55kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Y-Dilution Ratio | "WB 1:500-2000. IHC 1:50-200. IF 1:50-200." |
| Specification | 50ul 100ul |
| Reactivity | Rat Mouse Human |
| Application | IF IHC WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with FSCN1 antibody diluted at 1:1000;Lane: U251,HeLa,NCI-H460,HepG2,SH-SY5Y,Mouse brain,Mouse spinal cord.
Immunohistochemistry of paraffin-embedded Mouse testis with FSCN1 antibody diluted at 1:100.
Immunofluorescence analysis of C6 cells using FSCN1 antibody diluted at 1:100.
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