English Name |
Anti-ACHE Polyclonal Antibody |
Chinese Name |
乙酰胆碱酯酶抗体 |
Target |
ACHE |
Synonym |
Acetylcholinesterase, Acetylcholine acetylhydrolase, Acetylcholinesterase YT blood group, ACHE protein, Apoptosis related acetylcholinesterase, ARACHE, N ACHE, N-ACHE, YT, Yt blood group, ACES_HUMAN |
Backgroud |
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. |
Swiss Prot |
P22303 |
Gene ID |
43 |
Subcellular Localization |
Cytoplasm Nucleus Cell membrane |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
68kDa |
Dilution Ratio |
WB 1:500-2000.IF 1:50-200 |
Immunogen |
Recombinant protein of human ACHE |
Public Immunogen Range |
398-617aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IF |
Specification |
50ul 100ul |