English Name |
Anti-ROR2 Polyclonal Antibody |
Chinese Name |
受体酪氨酸激酶样孤儿素受体2抗体 |
Target |
ROR2 |
Synonym |
BDB, BDB1, Brachydactyly type B, EC 2.7.10.1, MGC163394, Neurotrophic tyrosine kinase, Neurotrophic tyrosine kinase, receptor related 2, NTRKR2, Receptor tyrosine kinase-like orphan receptor 2, receptor-related 2, ROR2, ROR2_HUMAN, Tyrosine protein kinase transmembrane receptor ROR2, Tyrosine-protein kinase transmembrane receptor Ror2 |
Backgroud |
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. |
Swiss Prot |
Q01974 |
Gene ID |
4920 |
Subcellular Localization |
Cell membrane Single-pass type I membrane protein |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
105kDa |
Dilution Ratio |
WB 1:500-1000. IHC 1:100-200. |
Immunogen |
A synthetic peptide of human ROR2 |
Public Immunogen Range |
100-200aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IHC |
Specification |
50ul 100ul |