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Anti-TDG Polyclonal Antibody

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Cat.No：K004187P Solarbio

Reactivity：Rat,Mouse,Human

Application： WB

Storage：Store at -20℃. Avoid freeze/thaw cycles.

Host：Rabbit

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Product Information

Name	Anti-TDG Polyclonal Antibody
Host	Rabbit
Clone Type	Polyclonal Antibody
Subtype	IgG
Dilution Ratio	WB 1:500-1000.
Target	TDG
Background	The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.
Swiss Prot	Q13569
Gene ID	6996
Subcellular Location	Nucleus
Immunogen	Recombinant protein of human TDG
Public Immunogen Range	1-160aa
Calculated MW	46kDa
Purification Method	Affinity purification
Storage Buffer	PBS with 0.02% sodium azide，50% glycerol，pH7.3.
Storage	Store at -20℃. Avoid freeze/thaw cycles.
Piece	Piece
Specification	50ul 100ul
Reactivity	Rat Mouse Human
Application	WB

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Kindly reminder：Quick spin before use. If you have any questions, please contact us.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.