English Name |
Anti-KCND2 Polyclonal Antibody |
Chinese Name |
钾电压门控通道Shal相关亚家族成员2抗体 |
Target |
KCND2 |
Synonym |
Potassium voltage-gated channel subfamily D member 2, KCD2, KCND 2, KCND2, KCND2_HUMAN, KIAA1044, Potassium voltage gated channel Shal related subfamily member 2, RK 5, RK5, Voltage gated potassium channel Kv4.2, Voltage gated potassium channel subunit Kv4.2, Voltage sensitive potassium channel, voltage-gated potassium channel Kv4.2, Voltage-gated potassium channel subunit Kv4.2, voltage-sensitive potassium channel |
Backgroud |
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. |
Swiss Prot |
Q9NZV8 |
Gene ID |
3751 |
Subcellular Localization |
Cell junction Cell membrane Cell projection Multi-pass membrane protein Perikaryon dendrite dendritic spine postsynaptic cell membrane synapse |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
71kDa |
Dilution Ratio |
WB 1:1000-5000. |
Immunogen |
Recombinant protein of human KCND2 |
Public Immunogen Range |
501-630aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat |
Application |
WB |
Specification |
50ul 100ul |