English Name |
Anti-CD207 Polyclonal Antibody |
English Name |
Anti-CD207 Polyclonal Antibody |
Chinese Name |
CD207分子抗体 |
Chinese Name |
CD207分子抗体 |
Target |
CD207 |
Synonym |
C-type lectin domain family 4 member K, CD207 antigen, langerin, C type lectin domain family 4 member K, CD 207, CD207, CD207 antigen, CD207 molecule, CLEC 4K, CLEC4K, Langerhans cell specific c type lectin, RGD1565913, CLC4K_HUMAN |
Host |
Rabbit |
Backgroud |
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. |
Clone Type |
Polyclonal Antibody |
Swiss Prot |
Q9UJ71 |
Subtype |
IgG |
Gene ID |
50489 |
Subcellular Localization |
Membrane Single-pass type II membrane protein |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Dilution Ratio |
WB 1:500-1000. |
Subtype |
IgG |
Protein MW |
37kDa |
Dilution Ratio |
WB 1:500-1000. |
Immunogen |
Recombinant protein of human CD207 |
Public Immunogen Range |
69-328aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Target |
CD207 |
Synonyms |
C-type lectin domain family 4 member K, CD207 antigen, langerin, C type lectin domain family 4 member K, CD 207, CD207, CD207 antigen, CD207 molecule, CLEC 4K, CLEC4K, Langerhans cell specific c type lectin, RGD1565913, CLC4K_HUMAN |
Background |
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. |
Swiss Prot |
Q9UJ71 |
Gene ID |
50489 |
Subcellular Location |
Membrane Single-pass type II membrane protein |
Immunogen |
Recombinant protein of human CD207 |
Public Immunogen Range |
70-200aa |
Calculated MW |
37kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Unit |
Piece |
Unit |
Piece |
Specification |
50ul 100ul |
Application |
WB |
Cross-Reactivity |
Human Mouse Rat |
Application |
WB |
Specification |
50ul 100ul |