English Name |
Anti-CREB3 Polyclonal Antibody |
English Name |
Anti-CREB3 Polyclonal Antibody |
Target |
CREB3 |
Synonym |
LUMAN;LZIP;sLZIP |
Host |
Rabbit |
Backgroud |
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined. |
Clone Type |
Polyclonal Antibody |
Swiss Prot |
O43889 |
Subtype |
IgG |
Gene ID |
10488 |
Subcellular Localization |
Cytoplasm Endoplasmic reticulum membrane Membrane Nucleus Single-pass type II membrane protein |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Dilution Ratio |
WB 1:500-2000.IF 1:10-100 |
Subtype |
IgG |
Protein MW |
44kDa |
Dilution Ratio |
WB 1:500-2000.IF 1:10-100 |
Immunogen |
Recombinant protein of human CREB3 |
Public Immunogen Range |
1-230aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Target |
CREB3 |
Synonyms |
LUMAN;LZIP;sLZIP |
Background |
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined. |
Swiss Prot |
O43889 |
Gene ID |
10488 |
Subcellular Location |
Cytoplasm Endoplasmic reticulum membrane Membrane Nucleus Single-pass type II membrane protein |
Immunogen |
Recombinant protein of human CREB3 |
Public Immunogen Range |
1-230aa |
Calculated MW |
44kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Unit |
Piece |
Unit |
Piece |
Specification |
100ul |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IF |
Specification |
50ul 100ul |