English Name |
Anti-PDCD6 Polyclonal Antibody |
Chinese Name |
凋亡相关蛋白6抗体 |
Target |
PDCD6 |
Synonym |
ALG 2, ALG2, Apoptosis linked gene 2, Apoptosis linked gene 2 protein, Apoptosis-linked gene 2 protein, MA 3, MA3, MGC111017, MGC119050, MGC9123, PDCD 6, Pdcd6, PDCD6_HUMAN, PEF 1B, PEF1B, Probable calcium binding protein ALG 2, Probable calcium binding protein ALG2, Probable calcium-binding protein ALG-2, Programmed cell death 6, Programmed cell death protein 6, PS 2, PS2 |
Backgroud |
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. |
Swiss Prot |
O75340 |
Gene ID |
10016 |
Subcellular Localization |
Endoplasmic reticulum membrane Endosome Nucleus Nucleus membrane Peripheral membrane protein |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
22kDa |
Dilution Ratio |
WB 1:500-1000. IP 1:50-200. |
Immunogen |
Recombinant protein of human PDCD6 |
Public Immunogen Range |
1-191aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IP |
Specification |
50ul 100ul |