English Name |
Anti-ATP2B2 Polyclonal Antibody |
Chinese Name |
细胞膜钙转运ATP酶抗体 |
Target |
ATP2B2 |
Synonym |
ATP2B1, ATP2B2, ATP2B3, ATP2B4, ATPase Ca++ transporting plasma membrane 1, ATPase Ca++ transporting plasma membrane 2, ATPase Ca++ transporting plasma membrane 3, ATPase Ca++ transporting plasma membrane 4, Plasma membrane calcium transporting ATPase 1, Plasma membrane calcium transporting ATPase 2, Plasma membrane calcium transporting ATPase 3, Plasma membrane calcium transporting ATPase 4, PMCA1, PMCA2, PMCA3, PMCA4, AT2B2_HUMAN |
Backgroud |
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Swiss Prot |
Q01814 |
Gene ID |
491 |
Subcellular Localization |
Cell junction Cell membrane Multi-pass membrane protein synapse |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
137kDa |
Dilution Ratio |
WB 1:500-1000. |
Immunogen |
Recombinant protein of human ATP2B2 |
Public Immunogen Range |
1-80aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Mouse Rat |
Application |
WB |
Specification |
50ul 100ul |