English Name |
Anti-CARD11 Polyclonal Antibody |
Chinese Name |
凋亡加强结构域蛋白11抗体 |
Target |
CARD11 |
Synonym |
Bcl10 interacting maguk protein 3, BIMP 3, BIMP3, CAR11_HUMAN, CARD 11, CARD containing MAGUK protein 3, Card maguk protein 1, CARD-containing MAGUK protein 1, CARD11, CARD11 protein, Carma 1, CARMA1, Caspase recruitment domain containing protein 11, Caspase recruitment domain family member 11, Caspase recruitment domain-containing protein 11, MGC133069 |
Backgroud |
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. |
Swiss Prot |
Q9BXL7 |
Gene ID |
84433 |
Subcellular Localization |
Cytoplasm Membrane raft |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
133kDa |
Dilution Ratio |
WB 1:500-2000.IF 1:50-100 |
Immunogen |
Recombinant protein of human CARD11 |
Public Immunogen Range |
985-1154aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IF |
Specification |
50ul 100ul |