English Name |
Anti-COQ3 Polyclonal Antibody |
Chinese Name |
辅酶Q3同系物甲基转移酶抗体 |
Target |
COQ3 |
Synonym |
3 4 dihydroxy 5 hexaprenylbenzoate methyltransferase, bA9819.1, Coenzyme Q3 homolog methyltransferase (S. cerevisiae), Coenzyme Q3 homolog methyltransferase (yeast), Coenzyme Q3 homolog methyltransferase, COQ 3, DHHB methyltransferase, DHHB MT, DHHB MTase, DHHBMT, DHHBMTASE, Dihydroxyhexaprenylbenzoate methyltransferase, Hexaprenyldihydroxybenzoate methyltransferase, Hexaprenyldihydroxybenzoate methyltransferase mitochondrial, Methyltransferase COQ3, |
Backgroud |
Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol. |
Swiss Prot |
Q9NZJ6 |
Gene ID |
51805 |
Subcellular Localization |
Matrix side Mitochondrion inner membrane Peripheral membrane protein |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
41kDa |
Dilution Ratio |
WB 1:500-2000.IF 1:50-200 |
Immunogen |
Recombinant protein of human COQ3 |
Public Immunogen Range |
50-369aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IF |
Specification |
50ul 100ul |