English Name |
Anti-NDUFV1 Polyclonal Antibody |
Chinese Name |
NADH脱氢酶(泛醌)黄素蛋白1,51 kDa抗体 |
Target |
NDUFV1 |
Synonym |
CI 51kD, CI-51kD, CI51KD, Complex I 51kD, Complex I-51kD, FLJ59059, mitochondrial, NADH dehydrogenase (ubiquinone) flavoprotein 1, NADH dehydrogenase [ubiquinone] flavoprotein 1, NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, NADH dehydrogenase flavoprotein 1, NADH ubiquinone oxidoreductase 51 kDa subunit, NADH ubiquinone oxidoreductase, NADH ubiquinone oxidoreductase core subunit V1, NADH-ubiquinone oxidoreductase 51 kDa subunit, NDUFV 1, ndufv1, NDUV1_HUMAN, UQOR1 |
Backgroud |
The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Swiss Prot |
P49821 |
Gene ID |
4723 |
Subcellular Localization |
Mitochondrion |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
51kDa |
Dilution Ratio |
WB 1:500-2000.IHC 1:50-200. |
Immunogen |
Recombinant protein of human NDUFV1 |
Public Immunogen Range |
72-420aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IHC |
Specification |
50ul 100ul |