English Name |
Anti-TGFB3 Polyclonal Antibody |
Chinese Name |
转移生长因子β3(TGFβ3)抗体 |
Target |
TGFB3 |
Synonym |
ARVD,ARVD1,FLJ16571,LDS5,MGC105479,MGC118722,prepro-transforming growth factor beta-3,RNHF,TGF beta 3,TGF beta3,TGF-beta-3,TGFB 3,Tgfb3,TGFB3_HUMAN,transforming growth factor beta 3,Transforming growth factor beta-3 |
Backgroud |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. |
Swiss Prot |
P10600 |
Gene ID |
7043 |
Subcellular Localization |
Secreted |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
47kDa |
Dilution Ratio |
WB 1:500-2000. IHC 1:50-200. |
Immunogen |
Recombinant protein of human TGFB3 |
Public Immunogen Range |
25-300aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IHC |
Specification |
50ul 100ul |