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SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
K005929P-100ul	Inquiry	Inquiry	Inquiry	Inquiry
K005929P-50ul	Inquiry	Inquiry	Inquiry	Inquiry

English Name	Anti-BCCIP Polyclonal Antibody
Chinese Name	乳腺癌易感基因2和p21蛋白抑制因子抗体
Target	BCCIP
Synonym	bccip, BCCIP_HUMAN, BCCIPalpha, BCCIPbeta, BRCA2 and CDKN1A interacting protein, BRCA2 and CDKN1A-interacting protein, BRCA2 and Cip1/p21 interacting protein, Cdk inhibitor p21 binding protein, P21 and CDK associated protein 1, P21- and CDK-associated protein 1, Protein TOK-1, Protein TOK1, TOK 1, TOK 1alpha, TOK 1beta, TOK1
Backgroud	This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
Swiss Prot	Q9P287
Gene ID	56647
Subcellular Localization	Nucleus
Host	Rabbit
Clone Type	Polyclonal Antibody
Subtype	IgG
Protein MW	36kDa
Dilution Ratio	WB 1:500-2000. IHC 1:100-200.
Immunogen	Recombinant protein of human BCCIP
Public Immunogen Range	1-314aa
Purification Method	Affinity purification
Storage Buffer	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage	Store at -20℃, avoid freeze/thaw cycles.
Unit	Piece
Cross-Reactivity	Human Mouse Rat
Application	WB IHC
Specification	50ul 100ul