English Name |
Anti-Phospho-CDK1-Y15 Polyclonal Antibody |
Chinese Name |
周期蛋白依赖性激酶1抗体 |
Target |
Phospho-CDK1-Y15 |
Synonym |
Cdc 2, Cdc2, CDC28A, CDK 1, CDK-1, CDK1_HUMAN, CDKN1, CELL CYCLE CONTROLLER CDC2, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, Cell division protein kinase 1, Cell Divsion Cycle 2 Protein, Cyclin Dependent Kinase 1, Cyclin-dependent kinase 1, DKFZp686L20222, MGC111195, p34 Cdk1, p34 protein kinase, P34CDC2 |
Backgroud |
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Swiss Prot |
P06493 |
Gene ID |
983 |
Subcellular Localization |
Cytoplasm Mitochondrion Nucleus centrosome cytoskeleton microtubule organizing center spindle |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
34kDa |
Dilution Ratio |
WB 1:500-1000.IHC 1:50-200.IF 1:50-100.IP 1:50-100 |
Immunogen |
A phospho specific peptide corresponding to residues surrounding Y15 of human CDK1 |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IHC IF IP |
Specification |
50ul 100ul |