English Name |
Anti-DUSP10 Polyclonal Antibody |
Chinese Name |
双特异性磷酸酶10抗体 |
Target |
DUSP10 |
Synonym |
Dual specificity phosphatase 10, Dual specificity phosphatase MKP 5, Dual specificity phosphatase MKP5, Dual specificity protein phosphatase 10, DUS10_HUMAN, DUSP 10, DUSP10, DUSP10 protein, MAP kinase phosphatase 5, Mitogen activated protein kinase phosphatase 5, Mitogen-activated protein kinase phosphatase 5, MKP 5, MKP-5, MKP5, Serine/threonine specific protein phosphatase, |
Backgroud |
Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus.? |
Swiss Prot |
Q9Y6W6 |
Gene ID |
11221 |
Subcellular Localization |
Cytoplasm |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
53kDa |
Dilution Ratio |
WB 1:200-1000. IHC 1:10-100. |
Immunogen |
Recombinant protein of human DUSP10 |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Mouse |
Application |
WB IHC |
Specification |
50ul 100ul |