English Name |
Anti-IDH3B Polyclonal Antibody |
Chinese Name |
异柠檬酸脱氢酶3 (NAD+) β抗体 |
Target |
IDH3B |
Synonym |
FLJ11043, H-IDHB, IDH3B, IDH3B_HUMAN, Isocitrate dehydrogenase [NAD] subunit beta, Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, isocitrate dehydrogenase 3, beta subunit, Isocitric dehydrogenase, Isocitric dehydrogenase subunit beta, MGC903, mitochondrial, NAD(+)-specific ICDH, NAD(+)-specific ICDH subunit beta, NAD+-specific isocitrate dehydrogenase b subunit, NAD+-specific isocitrate dehydrogenase beta, |
Backgroud |
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Swiss Prot |
O43837 |
Gene ID |
3420 |
Subcellular Localization |
Cytoplasm |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
42kDa |
Dilution Ratio |
WB 1:500-2000. IHC 1:25-100. |
Immunogen |
Recombinant protein of human IDH3B |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IHC |
Specification |
50ul 100ul |