English Name |
Anti-ADAMTS5 Polyclonal Antibody |
Chinese Name |
软骨蛋白聚糖抗体 |
Target |
ADAMTS5 |
Synonym |
ADAMTS5, A disintegrin and metalloproteinase with thrombospondin motifs 5, A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 5, A Disintigrin And Metalloproteinase with ThromboSpondin motif-5, ADAM metallopeptidase with thrombospondin type 1 motif 5, ADAM TS 11, ADAM TS 5, ADAM TS5, ADAMTS 11, ADAMTS 5, ADAMTS11, ADMP 2, ADMP2, Aggrecanase 2, aggrecanase-2, FLJ36738, Implantin, ThromboSpondin motif-5 |
Backgroud |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. |
Swiss Prot |
Q9UNA0 |
Gene ID |
11096 |
Subcellular Localization |
Cytoplasm |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
102kDa |
Dilution Ratio |
WB 1:200-1000. |
Immunogen |
A synthetic peptide of human ADAMTS5 |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Mouse |
Application |
WB |
Specification |
50ul 100ul |