English Name |
Anti-ANP32E Polyclonal Antibody |
Chinese Name |
富含亮氨酸样酸性核蛋白抗体 |
Target |
ANP32E |
Synonym |
Acidic (leucine rich) nuclear phosphoprotein 32 family member E, Acidic leucine-rich nuclear phosphoprotein 32 family member E, AN32E_HUMAN, ANP32E, Cerebellar postnatal development protein 1, LANP like protein, LANP-L, LANP-like protein, LANPL, Leucine rich acidic nuclear protein like, MGC5350 |
Backgroud |
The Anp32 family consists of 32 evolutionarily-conserved proteins and is included within the superfamily of leucine-rich repeat (LRR) proteins. Leucine-rich acidic nuclear protein-like (LANPL), also called ANP32E or Cpd1, is a member of the Anp32 family. LANPL is located in the cytoplasm of peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney. It has also been detected in the nucleus, cytoplasm and membrane of multiple brain regions. Upon phosphorylation, LANPL colocalizes and inhibits protein phosphatase 2A (PP2A), but does not inhibit PP1. LANPL modulates cell signalling and transduction of gene expression to regulate the morphology and dynamics of the cytoskeleton, cell adhesion, neural development and cerebellar morphogenesis. |
Swiss Prot |
Q9BTT0 |
Gene ID |
81611 |
Subcellular Localization |
Cytoplasm Nucleus |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
31kDa |
Dilution Ratio |
WB 1:500-2000. IHC 1:50-200. |
Immunogen |
A synthetic peptide of human ANP32E |
Public Immunogen Range |
255-268aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IHC |
Specification |
50ul 100ul |