English Name |
Anti-UHRF2 Polyclonal Antibody |
Chinese Name |
环指蛋白107抗体 |
Target |
UHRF2 |
Synonym |
E3 ubiquitin-protein ligase UHRF2, Np95 like RING finger protein, Np95-like ring finger protein, Np95/ICBP90 like RING finger protein, Np95/ICBP90-like RING finger protein, Nuclear protein 97, Nuclear zinc finger protein Np97, RING finger protein 107, RNF 107, RP11-472F14.2, Ubiquitin like containing PHD and RING finger domains protein 2, Ubiquitin-like PHD and RING finger domain-containing protein 2, Ubiquitin-like-containing PHD and RING finger domains protein 2, Uhrf2, UHRF2_HUMAN |
Backgroud |
This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. |
Swiss Prot |
Q96PU4 |
Gene ID |
115426 |
Subcellular Localization |
Nucleus |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
90/56kDa |
Dilution Ratio |
WB 1:500-2000. IHC 1:50-200. |
Immunogen |
A synthetic peptide of human UHRF2 |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Mouse |
Application |
WB IHC |
Specification |
50ul 100ul |