English Name |
Anti-ADAM15 Polyclonal Antibody |
Chinese Name |
去整合素样金属蛋白酶15抗体 |
Target |
ADAM15 |
Synonym |
A disintegrin and metalloproteinase domain 15, ADA15_HUMAN, ADAM 15, ADAM metallopeptidase domain 15, Adam15, and cysteine-rich protein 15, Disintegrin and metalloproteinase domain-containing protein 15, disintegrin-like, EC 3.4.24., MDC 15, MDC-15, MDC15, Metalloprotease RGD disintegrin protein, Metalloproteinase like disintegrin like and cysteine rich protein 15, Metalloproteinase-like, Metargidin |
Backgroud |
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Swiss Prot |
Q13444 |
Gene ID |
8751 |
Subcellular Localization |
Cytoplasm |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
93/86kDa |
Dilution Ratio |
WB 1:500-2000. IHC 1:25-100. |
Immunogen |
Recombinant protein of human ADAM15 |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IHC |
Specification |
50ul 100ul |