Anti-PARP Monoclonal Antibody
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Cat.No：K200026M Solarbio
Reactivity：Human
Application： WB;IHC
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Host：Mouse
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Inhibitors & Antagonists & Agonists
PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
Metabolic Enzyme & Protease
Autophagy
ER Stress
Cell Cycle
Cytoskeleton
DNA Damage & DNA Repai
Epigenetics
Ubiquitin
JAK/STAT
GPCR & G Protein
Neuronal Signal Pathway
MAPK
NF-κB
Membrane Transporter & Ion Channel
TGF-β/Smad
Hippo
Antibody-drug Conjugate/ADC Related
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Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
Sterilization & Filtration Instruments
PCR Instrument & Light Glue Instrument
Spectrophotometer
Centrifuge
Shaker
Vacuum Pump
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> Antibodies > Loading Control Antibodies > Nucleus > Anti-PARP Monoclonal Antibody
Product Information
Experimental Images
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Product Information
| Name | Anti-PARP Monoclonal Antibody |
| Host | Mouse |
| Clone Type | Monoclonal Antibody |
| Subtype | IgG1 |
| Clone Number | M3 |
| Dilution Ratio | WB 1:2000-4000. IHC 1:50-200. |
| Target | PARP |
| Background | Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate. |
| Swiss Prot | P09874 |
| Gene ID | 142 |
| Subcellular Location | Nucleus nucleolus |
| Immunogen | A synthetic peptide coupled to KLH |
| Calculated MW | 116kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Piece | Piece |
| Specification | 50ul 100ul |
| Reactivity | Human |
| Application | WB;IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Experimental Images
Immunohistochemistry of paraffin-embedded Human stomach cancer with PARP antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Human prostate cancer with PARP antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Human ovarian cancer with PARP antibody diluted at 1:200
Western blot analysis with PARP antibody diluted at 1:3000;Lane: L-02
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