English Name |
Anti-ALDOB Polyclonal Antibody |
Chinese Name |
醛缩酶2抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:500-2000.IHC 1:50-200. |
Target |
ALDOB |
Synonyms |
ALDB, ALDO B, ALDO2, ALDOB, ALDOB_HUMAN, Aldolase 2, Aldolase B, Aldolase B fructose bisphosphate, Aldolase2, AldolaseB, EC 4.1.2.13, Fructose bisphosphate aldolase B, Fructose-bisphosphate aldolase B, Liver type aldolase, Liver-type aldolase |
Background |
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. |
Swiss Prot |
P05062 |
Gene ID |
229 |
Subcellular Location |
Cytoplasm centriolar satellite centrosome cytoskeleton microtubule organizing center |
Immunogen |
A synthetic peptide of human ALDOB |
Calculated MW |
39kDa |
Purification Method |
Affinity purification |
Storage Buffer |
pH7.4 PBS,0.05% NaN3,40% Glycerol. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Unit |
Piece |
Specification |
50ul 100ul |