English Name |
Anti-PDCD6IP Polyclonal Antibody |
Chinese Name |
调亡诱导因子6相互作用蛋白/多巴胺受体相互作用蛋白4抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:200-1000. |
Target |
PDCD6IP |
Synonyms |
AIP1, ALG 2 interacting protein 1, ALG-2-interacting protein 1, ALG2 interacting protein X, Alix, Apoptosis linked gene 2 interacting protein X, Dopamine receptor interacting protein 4, DRIP4, HP95, KIAA1375, MGC17003, PDC6I_HUMAN, PDCD6 interacting protein, PDCD6-interacting protein, PDCD6IP, Programmed cell death 6 interacting protein, Programmed cell death 6-interacting protein |
Background |
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. |
Swiss Prot |
Q8WUM4 |
Gene ID |
10015 |
Subcellular Location |
Cytoplasm Melanosome centrosome cytoskeleton cytosol microtubule organizing center |
Immunogen |
A synthetic peptide of human PDCD6IP |
Calculated MW |
96kDa |
Purification Method |
Affinity purification |
Storage Buffer |
pH7.4 PBS,0.05% NaN3,40% Glycerol. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Unit |
Piece |
Specification |
50ul 100ul |
Application |
WB |