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My CartReactivity：Mouse,Human
Application：IHC,WB,ELISA
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：23657
Host：Rabbit
Qty：
Size：
| Name | Anti-SLC7A11 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:1000-5000. IHC 1:50-100. ELISA 1:5000-10000. |
| Target | SLC7A11 |
| Background | This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. |
| Swiss Prot | Q9UPY5 |
| Gene ID | 23657 |
| Subcellular Location | Cell membrane |
| Immunogen | A synthetic peptide of human SLC7A11 |
| Public Immunogen Range | 196-230aa |
| Calculated MW | 55kDa |
| Purification Method | Affinity purification |
| Storage Buffer | pH7.4 PBS，0.05% NaN3，40% Glycerol. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Mouse Human |
| Application | WB ELISA IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded Human cervical cancer with SLC7A11 antibody diluted at 1:100.
Western blot analysis with SLC7A11 antibody diluted at 1:3000;Lane: HepG2,293T.
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Click to check >>Author：Yu Zhang, Xiyou Du, Zhijing He, Shan Gao, Lei Ye, Jianbo Ji, Xiaoye Yang, Guangxi Zhai
IF：17.1000
Publish_to：ACS Nano
PMID：37272777
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Click to check >>Author：You J H
IF：11.1610
Publish_to：Journal of Experimental & Clinical Cancer Research
PMID：34749765
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