English Name |
Anti-EFNB3 Polyclonal Antibody |
Chinese Name |
酪氨酸蛋白激酶B3抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:200-1000. IHC 1:25-100. ELISA 1:1000-10000. |
Target |
EFNB3 |
Synonyms |
Ephrin B3, EphrinB3 antibody EPH related receptor transmembrane ligand ELK L3, EPH related receptor tyrosine kinase ligand 8, Ephrin B3, EphrinB3, EPLG 8, LERK 8, EFL 6, EFL6, EFNB 3, EFNB3, EFNB3_HUMAN, EPH related receptor transmembrane ligand ELKL3, EPH-related receptor transmembrane ligand ELK-L3, EPH-related receptor tyrosine kinase ligand 8, Ephrin-B3, EPLG8, LERK-8, LERK8 |
Background |
EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. |
Swiss Prot |
Q15768 |
Gene ID |
1949 |
Subcellular Location |
Cell membrane |
Immunogen |
A synthetic peptide of human EFNB3 |
Calculated MW |
36kDa |
Purification Method |
Affinity purification |
Storage Buffer |
pH7.4 PBS,0.05% NaN3,40% Glycerol. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Unit |
Piece |
Specification |
50ul 100ul |