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My Cart> Antibodies > Primary Antibodies > Anti-CATD (light chain,Cleaved-Gly65) Polyclonal AntibodyReactivity：Human
Application：WB,IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：1509
Host：Rabbit
Qty：
Size：
| Name | Anti-CATD (light chain,Cleaved-Gly65) Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:10000-15000. IHC 1:50-200. |
| Target | CATD (light chain,Cleaved-Gly65) |
| Background | This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. |
| Swiss Prot | P07339 |
| Gene ID | 1509 |
| Subcellular Location | Lysosome Melanosome Secreted extracellular space |
| Immunogen | CatD, CATD_HUMAN, Cathepsin D, Cathepsin D heavy chain, CD, Ceroid lipofuscinosis neuronal 10, CLN10, CPSD, ctsd, Epididymis secretory sperm binding protein Li 130P, HEL S 130P, Lysosomal aspartyl peptidase, Lysosomal aspartyl protease, MGC2311,"A synthetic peptide of human CATD (light chain,Cleaved-Gly65) |
| Public Immunogen Range | 30-80/412aa |
| Calculated MW | 45kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with CATD (light chain,Cleaved-Gly65) antibody diluted at 1:1000;Lane: MCF7,A431.
Immunohistochemistry of paraffin-embedded Human breast cancer with CATD (light chain,Cleaved-Gly65) antibody diluted at 1:100.
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