Application: ELISA
Reactivity:Canine
Sensitivity:5pg/mL
Storage:2-8℃,6 months
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Application: ELISA
Reactivity:Canine
Sensitivity:5pg/mL
Storage:2-8℃,6 months
Chinese Name | 犬瘦素检测试剂盒 |
English Name | Canine Leptin ELISA Kit |
Synonyms | FLJ94114; LEP; leptin (murine obesity homolog); leptin (obesity homolog, mouse); Leptin; OB; Obese protein; obese, mouse, homolog of; Obesity factor; OBOBS |
Storage | 2-8℃,6 months |
Detection Target | Leptin |
Sample Type | Serum,Plasma,Cell Culture Supernatant |
Reactivity | Canine |
Application | ELISA |
Quantitative/Qualitative | Quantitative |
Detection Range | 25-1600pg/mL |
Sensitivity | 5pg/mL |
Precision | Both intra-plate and inter-plate variation coefficients were less than 10% |
Recovery | 80%-120% |
Swiss Prot | O02720 |
Gene ID | 403616 |
Background | Adipose cells produce and secrete numerous physiologically important proteins,such as lipoprotein lipase (LPL),leptin and adiponectin protein of 30 kDa. Adiponectin is a circulating protein that is secreted exclusively by differentiated adipocytes. During adipocyte differentiation,mRNA levels of Adiponectin have been shown to be induced over 100-fold. Studies indicate that Adiponectin enhances the ability of sub-physiological levels of insulin to suppress glucose production,thus linking adipose tissue to whole body glucose regulation. Adiponectin function appears to be regulated by phosphatidylinositol-3-kinase (PI3-K) since Adiponectin secretion is blocked by pharmacologic inhibitors of this kinase. mRNA levels of Adiponectin have been shown to be significantly reduced in adipose tissue of obese patients with Type 2 diabetes relative to control subjects. Structural similarities to TNFalpha suggests that Adiponectin may play a role in pathogenesis of insulin resistance in Type 2 diabetes. Because Adiponectin is down-regulated in various forms of obesity and its structural similarity to TNFalpha,it is currently being investigated as an important regulator of whole body energy homeostasis. |
Unit | Kit |
Specification | 48T 96T |