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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > MAPK > Asiatic acidCAS：464-92-6
Molecular Formula：C30H48O5
Molecular Weight：488.7
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 464-92-6 |
| Name | Asiatic acid |
| Molecular Formula | C30H48O5 |
| Molecular Weight | 488.7 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 482-720-9 |
| MDL | MFCD00238541 |
| SMILES | O=C([C@]12CC[C@@H](C)[C@H](C)[C@@]1([H])C3=CC[C@]4([H])[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@]5([H])CC[C@@]4(C)[C@]3(C)CC2)O |
| InChIKey | JXSVIVRDWWRQRT-UYDOISQJSA-N |
| InChI | InChI=1S/C30H48O5/c1-17-9-12-30(25(34)35)14-13-28(5)19(23(30)18(17)2)7-8-22-26(3)15-20(32)24(33)27(4,16-31)21(26)10-11-29(22,28)6/h7,17-18,20-24,31-33H,8-16H2,1-6H3,(H,34,35)/t17-,18+,20-,21-,22-,23+,24+,26+,27+,28-,29-,30+/m1/s |
| PubChem CID | 119034 |
| Target Point | p38MAPK |
| Passage | MAPK |
| Background | It is a pentacyclic triterpenoid that induces apoptosis in melanoma cells. Also has anti-inflammatory activity. |
| Biological Activity | Asiatic acid， a pentacyclic triterpene found in Centella asiatica， induces apoptosis in melanoma cells. Asiatic acid has the potential for skin cancer treatment[1]. Asiatic acid also has anti-inflammatory activities[2]. |
| Data Literature Source | [1]. Park BC，et al. Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells. Cancer Lett. 2005 Jan 31;218(1):81-90. [2]. Huang SS，et al. Antinociceptive activities and the mechanisms of anti-inflammation of asiatic Acid in mice. Evid Based Complement Alternat Med. 2011;2011:895857. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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