Your Position: Home > Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > Abrine

Abrine

Manual Download

Cat.No：IA1140 Solarbio

CAS：21339-55-9

Molecular Formula：C₁₂H₁₄N₂O₂

Molecular Weight：218.25

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥95%

Appearance：White to off-white Solid

Qty：

Size：

Add to cart

Product Information Experimental Images Related Products Related Paper Technical Q&A

Product Information

CAS	21339-55-9
Name	Abrine
Molecular Formula	C₁₂H₁₄N₂O₂
Molecular Weight	218.25
Solubility	Soluble in DMSO
Purity	HPLC≥95%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 208-388-5
MDL	MFCD00467133
SMILES	O=C(O)[C@@H](N)CC1=CN(C)C2=C1C=CC=C2
InChIKey	ZADWXFSZEAPBJS-JTQLQIEISA-N
InChI	InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m0/s1
PubChem CID	676159
Target Point	Others
Passage	Others
Background	Abrine is an indoleamine-2,3-dioxygenase (IDO) inhibitor.
Biological Activity	1-Methyl-L-tryptophan is an inhibitor of indoleamine 2，3-dioxygenase (IDO).1-L-MT， an IDO inhibitor， prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells.[1-2]
Data Literature Source	[1]. Huang GL，et，al. PEG-Poly(1-Methyl-l-Tryptophan)-Based Polymeric Micelles as Enzymatically Activated Inhibitors of Indoleamine 2，3-Dioxygenase. Nanomaterials (Basel). 2019 May 9;9(5):719. [2]. Liu X，et，al. 1-L-MT，an IDO inhibitor，prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells. Int J Cancer. 2018 Sep 15;143(6):1516-1529.
Unit	Bottle
Specification	10mg 20mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.