CAS |
102130-43-8 |
Chinese Name |
苍术苷钾盐 |
English Name |
Atractyloside potassium salt |
Purity |
HPLC≥98% |
Unit |
Bottle |
Molecular Formula |
C30H44K2O16S2 |
Molecular Weight |
802.99 |
Appearance |
White to off-white solid |
Storage |
Powder : 2-8℃, 2 years; In solvent(mother liquid): -20℃, 1 month; -80℃, 6 months |
Solubility |
Soluble in water/DMSO |
MDL |
MFCD00078810 |
InChIKey |
IUCNQFHEWLYECJ-VCQILIGCSA-L |
InChI |
InChI=1S/C30H46O16S2.2K/c1-14(2)9-22(32)44-25-24(46-48(39,40)41)23(45-47(36,37)38)20(13-31)43-28(25)42-17-10-18(27(34)35)19-7-8-30-11-16(15(3)26(30)33)5-6-21(30)29(19,4)12-17;;/h14,16-21,23-26,28,31,33H,3,5-13H2,1-2,4H3,(H,34,35)(H,36,37,38)(H,39,40,41);;/q;2*+1/p-2/t16-,17-,18-,19-,20-,21+,23-,24+,25-,26+,28+,29-,30-;;/m1../s1 |
PubChem CID |
12299879 |
SMILES |
[H][C@@]12C(C(O)=O)C[C@@H](O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)OS(=O)(O[K])=O)OS(=O)(O[K])=O)OC(CC(C)C)=O)C[C@@]1(C)[C@@]4([H])[C@@]5([C@@H](O)C([C@H](CC4)C5)=C)CC2 |
Description |
Atractyloside potassium salt is a potent and specific inhibitor of mitochondrial ADP/ATP transport,) |
Target Point |
Others |
Passage |
Others |
Data Literature Source |
[1]. Yamaguchi N, Kagari T, Kasai M. Inhibition of the ryanodine receptor calcium channel in the sarcoplasmic reticulum of skeletal muscle by an ADP/ATP translocase inhibitor, atractyloside. Biochem Biophys Res Commun, 1999, 258(2): 247-251.
[2]. Pick-Kober KH, Schneider F. Proliferation, macromolecular synthesis and energy metabolism of in vitro grown Ehrlich ascites tumor cells after inhibition of ATP-ADP translocation by atractyloside. Eur J Cell Biol, 1984, 34(2): 323-329.
[3]. Malekova L, Kominkova V, Ferko M, et al. Bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. Biochim Biophys Acta, 2007, 1767(1): 31-44. |
Specification |
5mg 10mg 10mM*1mL in DMSO |