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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > Birch-MeCAS：119-36-8
Molecular Formula：C8H8O3
Molecular Weight：152.15
Storage：Store at 2-8℃，2 years
Purity：GC≥98%
Appearance：Colorless to light yellow Liquid
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| CAS | 119-36-8 |
| Name | Birch-Me |
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 |
| Solubility | Soluble in DMSO |
| Purity | GC≥98% |
| Appearance | Colorless to light yellow Liquid |
| Storage | Store at 2-8℃，2 years |
| Density | 1.174g/mL |
| EC | EINECS 204-317-7 |
| MDL | MFCD00002214 |
| SMILES | O=C(OC)C1=CC=CC=C1O |
| InChIKey | OSWPMRLSEDHDFF-UHFFFAOYSA-N |
| InChI | InChI=1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3 |
| PubChem CID | 4133 |
| Target Point | COX;TRPV |
| Passage | Immunology & Inflammation;Membrane Transporter&Ion Channel;Neuronal Signaling |
| Background | Birch-Me is a COX inhibitor and an agonist of TRPA1 and TRPV1. It has analgesic and anti-inflammatory activities. |
| Biological Activity | Methyl Salicylate (Wintergreen oil) 是一种局部镇痛和抗炎剂。 还用作食品和烟草制品中的农药，变性剂，香料成分和调味剂[1]。烟草中的 (SAR) 信号[2]。局部非甾体抗炎药 (NSAID)。 Methyl salicylate lactoside 是 COX 抑制剂[4]。 |
| Data Literature Source | [1]. Greene T，et al. A critical review of the literature to conduct a toxicity assessment for oral exposure to methyl salicylate. Crit Rev Toxicol. 2017 Feb;47(2):98-120. [2]. Park SW，et al. Methyl salicylate is a critical mobile signal for plant systemic acquired resistance. Science. 2007 Oct 5;318(5847):113-6. [3]. Lapczynski A，et al. Fragrance material review on methyl salicylate. Food Chem Toxicol. 2007;45 Suppl 1:S428-52. [4]. Xin W，et al. Methyl salicylate lactoside inhibits inflammatory response of fibroblast-like synoviocytes and joint destruction in collagen-induced arthritis in mice. Br J Pharmacol. 2014 Jul;171(14):3526-38. |
| Unit | Bottle |
| Specification | 1ml |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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