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Fraxin

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Cat.No：IF0320 Solarbio

CAS：524-30-1

Molecular Formula：C₁₆H₁₈O₁₀

Molecular Weight：370.31

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：Light yellow to yellow Solid

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Product Information

CAS	524-30-1
Name	Fraxin
Molecular Formula	C₁₆H₁₈O₁₀
Molecular Weight	370.31
Solubility	Soluble in DMSO ≥10mg/mL
Purity	HPLC≥98%
Appearance	Light yellow to yellow Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 208-355-5
MDL	MFCD00010093
SMILES	OC1=C(OC)C=C(C=C2)C(OC2=O)=C1O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO
Target Point	Phosphodiesterase (PDE)
Passage	Metabolic Enzyme&Protease
Background	Fraxin is a glycoside of ash lactone and has antioxidant, anti-inflammatory and anti-metastatic activities.
Biological Activity	Fraxin是白蜡树内酯的一种糖苷[1]，并具有抗氧化、抗炎和抗转移活性。Fraxin 通过抑制环腺苷酸磷酸二酯酶表现出抗氧化活性[2]。
Data Literature Source	[1]. Fraxin (50 mg/kg，p.o.) significantly blocks the CCl4-induced elevation of ALT and AST. Fraxin (10 and 50 mg/kg，p.o.) significantly reduces the GSSG levels (1.7±0.3 and 1.5±0.2 nM/g liver，respectively) compared with the GSSG levels of the CCl4-treated group[1]. [2]. Whang WK，et al. Natural compounds，fraxin and chemicals structurally related to fraxin protect cells from oxidative stress. Exp Mol Med. 2005 Oct 31;37(5):436-46.
Unit	Bottle
Specification	5mg 10mM*1mL in DMSO 10mg 20mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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