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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > HesperitinCAS：520-33-2
Molecular Formula：C16H14O6
Molecular Weight：302.29
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow Solid
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| CAS | 520-33-2 |
| Name | Hesperitin |
| Molecular Formula | C16H14O6 |
| Molecular Weight | 302.29 |
| Solubility | Soluble in DMSO ≥3mg/mL;Soluble in Ethanol ≥2mg/mL;Soluble in Water ＜1mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 208-290-2 |
| MDL | MFCD00075646 |
| SMILES | O=C1C[C@@H](C2=CC=C(OC)C(O)=C2)OC3=CC(O)=CC(O)=C13 |
| Target Point | Others |
| Passage | Others |
| Background | Hesperetin, a flavanone, is a potent, broad-spectrum UGT inhibitor. |
| Biological Activity | Hesperetin 是一种黄烷酮类物质，为有效的，广谱的人 UGT 抑制剂。[1-5] |
| Data Literature Source | [1]. Arya A，et al. Bioflavonoid hesperetin overcome bicalutamide induced toxicity by co-delivery in novel SNEDDS formulations: Optimization，in vivo evaluation and uptake mechanism. Mater Sci Eng C Mater Biol Appl. 2017 Feb 1;71:954-964. [2]. Liu D，et al. Inhibitory Effect of Hesperetin and Naringenin on Human UDP-Glucuronosyltransferase Enzymes: Implications for Herb-Drug Interactions. Biol Pharm Bull. 2016;39(12):2052-2059. [3]. Oo A，et al. In silico study on anti-Chikungunya virus activity of hesperetin. PeerJ. 2016 Oct 26;4:e2602. eCollection 2016. [4]. Shagirtha K，et al. Neuroprotective efficacy of hesperetin against cadmium induced oxidative stress in the brain of rats. Toxicol Ind Health. 2016 Nov 1. pii: 0748233716665301. [5]. Bai X，et al. The protective effect of the natural compound hesperetin against fulminant hepatitis in vivo and in vitro. Br J Pharmacol. 2017 Jan;174(1):41-56. |
| Unit | Bottle |
| Specification | 50mg 10mM*1mL in DMSO 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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