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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > Loxoprofen sodiumCAS：80382-23-6
Molecular Formula：C15H17NaO3
Molecular Weight：268.28
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 80382-23-6 |
| Name | Loxoprofen sodium |
| Molecular Formula | C15H17NaO3 |
| Molecular Weight | 268.28 |
| Solubility | Soluble in Water |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 1806241-263-5 |
| MDL | MFCD00941425 |
| SMILES | CC(C1=CC=C(CC2C(CCC2)=O)C=C1)C([O-])=O.[Na+] |
| Target Point | Others |
| Passage | Others |
| Background | Loxoprofen sodium is a nonselective COX inhibitor. |
| Biological Activity | Loxoprofen sodium 是一种具有镇痛、解热作用的非甾体类抗炎药。Loxoprofen sodium 是一种非选择性 COX 抑制剂，对 COX-1 和 COX-2 的 IC50 分别为 6.5 和 13.5 μM。[1-2] |
| IC50 | COX-1:6.5μM;COX-2:13.5μM [1-2] |
| Data Literature Source | [1]. Riendeau D，et al. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg Med Chem Lett. 2004;14(5):1201-1203. [2]. Paudel S，et al. Assessing Drug Interaction and Pharmacokinetics of Loxoprofen in Mice Treated with CYP3A Modulators. Pharmaceutics. 2019;11(9):479. Published 2019 Sep 16 |
| Unit | Bottle |
| Specification | 20mg 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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