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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > MAPK > MagnolinCAS：31008-18-1
Molecular Formula：C23H28O7
Molecular Weight：416.46
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 31008-18-1 |
| Name | Magnolin |
| Molecular Formula | C23H28O7 |
| Molecular Weight | 416.46 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD07783722 |
| SMILES | COC1=C(OC)C(OC)=CC([C@H]2OC[C@]3([H])[C@@H](C4=CC=C(OC)C(OC)=C4)OC[C@@]32[H])=C1 |
| Target Point | ERK |
| Passage | MAPK |
| Background | Magnolin targets ERK1 and ERK2, thereby inhibiting the Ras/ERKs/RSK2 signaling pathway. |
| Biological Activity | Magnolin 靶向作用于ERK1 和 ERK2，IC50s 分别为 87 nM 和 16.5 nM，从而抑制Ras/ERKs/RSK2信号通路[1]。 |
| Data Literature Source | [1]. Lee CJ，et al. Magnolin inhibits cell migration and invasion by targeting the ERKs/RSK2 signaling pathway. BMC Cancer. 2015 Aug 8;15:576. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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