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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > SesaminCAS：607-80-7
Molecular Formula：C20H18O6
Molecular Weight：354.35
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 607-80-7 |
| Name | Sesamin |
| Molecular Formula | C20H18O6 |
| Molecular Weight | 354.35 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00216134 |
| SMILES | C1(C2=CC=C(OCO3)C3=C2)OCC4C1COC4C5=CC=C(OCO6)C6=C5 |
| Target Point | Others |
| Passage | Others |
| Background | Sesamin, a lignan abundant in sesame oil, is a potent and selective inhibitor of delta 5 desaturase in polyunsaturated fatty acid biosynthesis. |
| Biological Activity | Sesamin 是一种在芝麻油中存在丰富的木脂素，是多不饱和脂肪酸生物合成中有效且选择性的 delta 5 去饱和酶抑制剂。Sesamin 对脑缺血具有有效的神经保护作用[1]。 |
| Data Literature Source | [1]. Cheng FC， et al. Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. Int J Biomed Sci. 2006 Sep; 2 (3) :284-8. |
| Unit | Bottle |
| Specification | 20mg 10mM*1mL in DMSO 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Suppression of cyclooxygenase 2 increases chemosensitivity to sesamin through the Akt?PI3K signaling pathway in lung cancer cells
Click to check >>Author：Fang Q. Zhu Y. Wang Q. Song M. Gao G. Zhou Z
IF：3.8180
Publish_to：Int J Mol Med
PMID：30365050
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