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CAS:69659-80-9
Storage:Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity:HPLC≥98%
Appearance:Red Solid
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Examples of using this product（for reference only）
In Vitro:
Cell(ARPE-19 cell lines; 10-30 μM Tanshinone IIA-sulfonic sodium/STS )：
Sodium tanshinone IIA sulfonate was purchased from Solarbio Company, and its purity was greater than 98%, as found by testing. It was diluted with DMEM basal medium to the fnal use concentration. In the experiment, escalating concentrations of STS (10 μM, 20 μM and 30 μM) were added to the medium, and 10 μM STS was chosen for the subsequent serious of experiments according to the fow cytometry analysis results using V-FITC/PI Staining. In the STS-intervention studies, ARPE-19 cells were seeded into 6-well plates at a concentration of 2×106 cells/mL. Te following day, H2O2, STS and autophagy inhibitor 3MA were diluted to their fnal use concentrations with DMEM basal medium, in accordance with the manufacturer’s instructions, and were added to the cells, alone or together for 24h. Te groups were follows: A: 0 μM H2O2, B: 200 μM H2O2, C: 200 μM H2O2+10 μM STS, D: 200 μM H2O2+5mM 3MA, E: 200μM H2O2+10 μM STS+5mM 3MA.
Reference：
Han D, Wu X, Liu L, Shu W, Huang Z. Sodium tanshinone IIA sulfonate protects ARPE-19 cells against oxidative stress by inhibiting autophagy and apoptosis. Sci Rep. 2018 Oct 11;8(1):15137. doi: 10.1038/s41598-018-33552-2. PMID: 30310136; PMCID: PMC6181947.
