Glycerol
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Cat.No：IG0910 Solarbio
CAS：56-81-5
Storage：Store at 2-8℃，2 years
Purity：GC≥99%
Appearance：Liquid
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Product Information
| CAS | 56-81-5 |
| Name | Glycerol |
| Molecular Formula | C3H8O3 |
| Molecular Weight | 92.09 |
| Purity | GC≥99% |
| Appearance | Liquid |
| Storage | Store at 2-8℃，2 years |
| Density | 1.25g/mL |
| EC | EINECS 200-289-5 |
| MDL | MFCD00675440 |
| SMILES | OCC(O)CO |
| InChIKey | PEDCQBHIVMGVHV-UHFFFAOYSA-N |
| InChI | InChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2 |
| PubChem CID | 753 |
| Target Point | Others |
| Passage | Others |
| Background | Glycerol is a clear, viscous liquid. |
| Biological Activity | Glycerol是透明，无色，粘稠的甜味液体。甘油可用于聚丙烯酰胺凝胶电泳的样品制备和凝胶形成。[1-3] |
| In Vitro | 甘油通常包含在聚丙烯酰胺凝胶中以防止在电泳期间核小体和其他蛋白质-DNA复合物的解离。含有甘油，分馏似乎主要基于颗粒质量和电荷。电泳过程中甘油的浓度强烈影响聚丙烯酰胺凝胶的分离特性[1]。甘油是油/脂肪加工的不可避免的副产物，无论其途径如何。已经在几种肠杆菌科的物种中详细研究了甘油的发酵代谢，例如弗氏柠檬酸杆菌和肺炎克雷伯菌。使用厌氧发酵将生物柴油生产过程中产生的丰富且价格低廉的甘油流转化为更高价值的产品，是实现生物燃料行业经济可行性的有希望的途径[2]。 |
| In Vivo | 甘油可以在大鼠模型中诱导急性肾衰竭。甘油或硝酸铀酰诱导的急性肾功能衰竭可减少某些药物的肝胆转运，调节药物向中枢神经系统的分布，并影响各种肝微粒体酶的活性[3]。 |
| Animal Experiment | 大鼠：在24小时的水剥夺后，通过将溶于盐水(50％v/v，10mL/kg)的甘油注射到腿部肌肉中，在230-300g雄性Wistar大鼠中诱导实验性急性肾衰竭[ 3]。 |
| Data Literature Source | [1]. Pennings S，et al. Effect of glycerol on the separation of nucleosomes and bent DNA in low ionic strengthpolyacrylamide gel electrophoresis. Nucleic Acids Res. 1992 Dec 25;20(24):6667-72. [2]. Yazdani SS，et al. Anaerobic fermentation of glycerol: a path to economic viability for the biofuelsindustry. Curr Opin Biotechnol. 2007 Jun;18(3):213-9. [3]. Huang ZH，et al. Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure. Eur J Pharmacol. 2000 Oct 20;406(3):453-60. |
| Unit | Piece |
| Specification | 500mg 1g |
Glycerol是透明，粘稠的液体。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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