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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > 9-MethoxycamptothecinCAS：19685-10-0
Molecular Formula：C21H18N2O5
Molecular Weight：378.384
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow Solid
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| CAS | 19685-10-0 |
| Name | 9-Methoxycamptothecin |
| Molecular Formula | C21H18N2O5 |
| Molecular Weight | 378.384 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 2017-001-1 |
| MDL | MFCD11975376 |
| SMILES | O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=CC(OC)=CC=C5N=C4C3=C2)=O |
| Target Point | Others |
| Passage | Others |
| Background | It is a natural biologically active analogue of camptothecin with anticancer activity. |
| Biological Activity | 10-Methoxycamptothecin is a natural bioactive derivative of camptothecin (CPT) isolated from Camptotheca acuminata， and has been confirmed to possess high anti-cancer properties. 10-Methoxycamptothecin has higher cytotoxicity than 10-hydroxycamptothecin by testing antitumor activity against 2774 cell lines[1]. |
| Data Literature Source | [1]. Zheng J，et al. Development and validation of a RP-HPLC method with fluorescence detection for simultaneous determination of 10-methoxycamptothecin and its metabolite 10-hydroxycamptothecin in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 201 |
| Unit | Piece |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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