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My Cart> Small Molecule Compounds > Anti-Infection > Anti-Bacterial > Salinomycin sodium saltCAS：55721-31-8
Molecular Formula：C42H69NaO11
Molecular Weight：772.98
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 55721-31-8 |
| Name | Salinomycin sodium salt |
| Molecular Formula | C42H69NaO11 |
| Molecular Weight | 772.98 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 611-309-0 |
| MDL | MFCD00167109 |
| SMILES | [H][C@]1([C@](C)(CC2)O[C@]32[C@H](O)C=C[C@]4(O[C@]([H])([C@@H](CC)C([C@@H](C)[C@@H](O)[C@H](C)[C@]5([H])O[C@]([C@@H](CC)C([O-])=O)([H])CC[C@@H]5C)=O)[C@@H](C)C[C@H]4C)O3)CC[C@@](CC)(O)[C@H](C)O1.[Na+] |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | Salinomycin sodium salt, a potassium ion carrier antibiotic, is a potent inhibitor of Wnt/β-catenin signaling and acts on the Wnt/Fzd/LRP complex, blocking WNT-induced phosphorylation of LRP6 and leading to degradation of LRP6 protein. |
| Biological Activity | Salinomycin sodium salt 是具有强大的抗菌 (anti-bacterial) 活性的抗球虫药，和靶向人类癌症干细胞的新型抗癌剂。[1-4] |
| Data Literature Source | [1]. Bi YL，et al. Salinomycin exhibits anti-angiogenic activity against human glioma in vitro and in vivo by suppressing the VEGF-VEGFR2-AKT/FAK signaling axis. Int J Mol Med. 2017 Mar 29 [2]. Rai G，et al. Evaluation of growth inhibitory response of Resveratrol and Salinomycin combinations against triple negative breast cancer cells. Biomed Pharmacother. 2017 Mar 11;89:1142-1151 [3]. Li R，et al. Salinomycin repressed the epithelial-mesenchymal transition of epithelial ovarian cancer cells via downregulating Wnt/β-catenin pathway. Onco Targets Ther. 2017 Feb 28;10:1317-132 [4]. Chung SS，et al. Salinomycin Abolished STAT3 and STAT1 Interactions and Reduced Telomerase Activity in Colorectal Cancer Cells. Anticancer Res. 2017 Feb;37(2):445-453 |
| Unit | Piece |
| Specification | 20mg 10mM*1mL in DMSO 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
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