CAS:220127-57-1
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to light yellow Solid
Examples of using this product(for reference only)
In Vivo:
Mice(Six-week-old nude mice; 10 mg/kg IM):
Murine xenograft modelSix-week-old nude mice were randomly assigned to four groups (n = 6). K562/IM cells(5x105) were stably transfected with sh-circ_0080145 or sh-NC and then injected subcutaneously into mice. After 7d of inoculation, the mice were treated with or without 10 mg/kg IM (Solarbio) every 4d. Tumor length and width were examined every 4d and tumor volume was calculated with the equation: (length · width2 )/2. Twentyseven days later, the mice were euthanized.
Reference:
Che H, Ding H, Jia X. circ_0080145 Enhances Imatinib Resistance of Chronic Myeloid Leukemia by Regulating miR-326/PPFIA1 Axis. Cancer Biother Radiopharm. 2020 Jun 27. doi: 10.1089/cbr.2020.3600. Epub ahead of print. PMID: 32598170.