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Your Position: Home > Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/RTK > Bcr-Abl > Imatinib Mesylate
Imatinib Mesylate

CAS:220127-57-1

Appearance:White to light yellow solid

Storage:Powder : 2-8℃, 2 years; In solvent(mother liquid): -20℃, 1 month; -80℃, 6 months

Purity:HPLC≥98%

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Imatinib Mesylate
Cat.No：
IF0480
Brand：
Solarbio
SKU Tongzhou Beijing Haidian Beijing Wuhan Guangzhou
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Product Information Related Products Related Paper COA Technical Q&A


Examples of using this product（for reference only）

In Vivo:

Mice（Six-week-old nude mice; 10 mg/kg IM）:

Murine xenograft modelSix-week-old nude mice were randomly assigned to four groups (n = 6). K562/IM cells(5x105) were stably transfected with sh-circ_0080145 or sh-NC and then injected subcutaneously into mice. After 7d of inoculation, the mice were treated with or without 10 mg/kg IM (Solarbio) every 4d. Tumor length and width were examined every 4d and tumor volume was calculated with the equation: (length · width2 )/2. Twentyseven days later, the mice were euthanized.

Reference：

Che H, Ding H, Jia X. circ_0080145 Enhances Imatinib Resistance of Chronic Myeloid Leukemia by Regulating miR-326/PPFIA1 Axis. Cancer Biother Radiopharm. 2020 Jun 27. doi: 10.1089/cbr.2020.3600. Epub ahead of print. PMID: 32598170.

Remark：
These protocols are for reference only. Solarbio does not independently validate these methods.

Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Experimental Images
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Che H, Ding H, Jia X. Cancer Biother Radiopharm. 2020 Jun 27.
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