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My CartCAS：402957-28-2
Molecular Formula：C36H53N7O6
Molecular Weight：679.85
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 402957-28-2 |
| Name | Telaprevir |
| Molecular Formula | C36H53N7O6 |
| Molecular Weight | 679.85 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 609-814-6 |
| MDL | MFCD11616089 |
| SMILES | O=C(N([C@@H]1C(N[C@H](C(C(NC2CC2)=O)=O)CCC)=O)C[C@@]3(CCC[C@@]31[H])[H])[C@@H](NC([C@@H](NC(C4=NC=CN=C4)=O)C5CCCCC5)=O)C(C)(C)C |
| Target Point | HCV Protease |
| Passage | Metabolic Enzyme/Protease |
| Background | Telaprevir is a potent and selective reversible HCV NS3-4A protease inhibitor. |
| Biological Activity | Telaprevir 是一种有效的选择性的可逆 HCV NS3-4A protease 抑制剂，作用于基因 1型 (H株) NS3 蛋白酶结构域和 NS4A 辅因子肽，Ki 为 7 nM。[1-3] |
| Data Literature Source | [1]. Lin K，et al. VX-950，a novel hepatitis C virus (HCV) NS3-4A protease inhibitor，exhibits potent antiviral activities in HCv replicon cells. Antimicrob Agents Chemother. 2006 May;50(5):1813-22. [2]. Perni RB，et al. Preclinical profile of VX-950，a potent，selective，and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine protease. Antimicrob Agents Chemother. 2006 Mar;50(3):899-909. [3]. Zhang X，et al. Discovery and evolution of aloperine derivatives as a new family of HCV inhibitors with novel mechanism. Eur J Med Chem. 2018 Jan 1;143:1053-1065. |
| Unit | Bottle |
| Specification | 10mg 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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