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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > Pizotifen malateCAS：5189/11/7
Molecular Formula：C23H27NO5S
Molecular Weight：429.53
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98.5%
Appearance：Solid
Qty：
Size：
| CAS | 5189/11/7 |
| Name | Pizotifen malate |
| Molecular Formula | C23H27NO5S |
| Molecular Weight | 429.53 |
| Solubility | Soluble in DMSO ≥2mg/mL(Need ultrasonic) |
| Purity | ≥98.5% |
| Appearance | Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 225-970-4 |
| MDL | MFCD01700978 |
| SMILES | O=C(O)C(O)CC(O)=O.CN1CC/C(CC1)=C2C3=CC=CC=C3CCC4=C\2C=CS4 |
| Target Point | Others |
| Passage | Others |
| Background | Pizotifen malate is a potent antagonist of the 5-HT2 receptor. |
| Biological Activity | Pizotifen malate 是 5-HT2 受体的有效拮抗剂，并对5-HT1C 有高亲和力。[1-3] |
| Data Literature Source | [1]. Mylecharane EJ，et al. 5-HT2 receptor antagonists and migraine therapy. J Neurol. 1991;238 Suppl 1:S45-52. [2]. Lin OA，et al. The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet function. PLoS One. 2014 Jan 23;9(1):e87026. [3]. Ujházy E，et al. Teratological and cytogenetical evaluation of two antihistamines (pipethiadene and pizotifen maleate) in mice. Agents Actions. 1988 Apr;23(3-4):376-8 |
| Unit | Bottle |
| Specification | 100mg 200mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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